Microbiological Aspects of Penicillin: IX. Cottonseed Meal as a Substitute for Corn Steep Liquor in Penicillin Production.

نویسندگان

  • J W Foster
  • H B Woodruff
  • D Perlman
  • L E McDaniel
  • B L Wilker
  • D Hendlin
چکیده

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The Effect of Medium Constituents

Since the discovery of the stimulating effect of corn steep liquor on penicillin fermentation, various lactosesteep liquor media have been used in penicillin fermentations. The requirements for a good penicillin fermentation are fulfilled by the steep liquor-lactose media by virtue of its composition (Johnson, 1952). The production of penicillin on a chemically defined medium (Jarvis and Johnso...

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(• ¯ " ‡ OE[ˆê • ")(‰ª • " • º ƒ') Some substances to promote the production of antibiotics were re ported already by many authors. According to Knight1) the use of corn steep liquor in the media of Penicillium chrysogenum increased the production of Penicillin. Koffler and others2) investigated on the promoting elements of corn steep liquor and reported that one element was the combination of ...

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Penicillin production in corn steep media with continuous carbohydrate addition.

The work reported here presents the results of an investigation into the replacement of lactose by glucose or by sucrose in a corn steep liquor medium for the production of penicillin. Previous work has established (Johnson, 1946) that glucose and sucrose are metabolized by Penicillium chrysogenum at a more rapid rate than is lactose. Also, it has been shown that a maximum rate of penicillin pr...

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Penicillin production by wild isolates of Penicillium chrysogenum in Pakistan

The present study was aimed at exploring the native wild isolates of Penicillium chrysogenum series in terms of their penicillin production potential. Apart from the standard medium, the efforts were made to utilize suitable agro-industrial wastes for the maximum yield of penicillin. Two series of P. chrysogenum were isolated from local sources and named as P. chrysogenum series UAF R1 and P. c...

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Organic acid metabolism of Penicillium chrysogenum. I. Lactate and acetate.

The media most useful for penicillin production contain corn-steep liquor (CSL), which has a high organic acid content. Such media usually contain about 5 mg./ml. lactic acid and rather less than 0-5 mg./ml. acetic acid. It has been found beneficial to include organic acids, especially the two mentioned, in synthetic media for penicillin production (Stone & Farrell, 1946; Jarvis & Johnson, 1947...

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عنوان ژورنال:
  • Journal of bacteriology

دوره 51 6  شماره 

صفحات  -

تاریخ انتشار 1946